Arrhythmia :

An Exciting & Challenging Field of Research

There’s more to cardiovascular science than you might think. Advance an area of massive medical importance.

We apply cutting edge biophysics methods to discover how nanoscale changes can make a life or death difference.

We use tissue-engineered models to understand how these biophysical phenomena affect myocytes, and we work with human patient myocytes to test whether our ideas will translate to patient care.

We use a lot of computer modeling from the atomic to whole heart scales to put this all together in a quantitative way.

Right now, a lot of our research focus is on drug therapy. Nearly 50% of arrhythmia patients report little to no effect from current medications. We’re committed to changing that – from a molecular to a patient level.

Supporting Our Research

Local funding, global perspective

External funding, through grant and fellowship applications, allows us to support these efforts. We also regularly publish our results in order to better collaborate with researchers and physicians worldwide and achieve our goal of improving patient health.

We currently occupy two lab spaces, located right next to each other. One is a more relaxed office area for data analysis and collaboration, while the other offers a full suite of molecular biology, electrophysiology and microscopy equipment.

We’re a diverse group, and strongly encourage those from a variety of different backgrounds to apply. A number of training grants and funding opportunities are available to students to enable them to fund their research.

Research Programs

Currently programs include several NIH-funded efforts focused on:

NIH-NHLBI, R01 HL150637
Post-Transcriptional Regulation of Myocardial Sodium Channels
NIH-NHLBI, R01 HL148803
Personalizing Class I anti-Arrhythmic Drug Therapy
NIH-NHLBI, R01 HL136553
Modulation of Cardiac NaV Channel Function and Electrophysiology by Interacting Molecules
NIH-NHLBI, R01 HL142301
Mechanism of BK Channel Gating